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Gene Review:

etf1 - eukaryotic translation termination factor 1

Xenopus laevis

Deblandre, G.A. et al., Ito, M. et al.

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High impact information on ETF1

This choice is under the control of lateral inhibition mediated by a Suppressor of Hairless-dependent Notch signaling pathway, in which X-Delta-1 is the putative ligand driving the selection process, and a new Enhancer-of-Split-related gene is an epidermal target of Notch signaling [1].

Biological context of ETF1

The CSL (CBF-1, Suppressor of Hairless, Lag-1) transcriptional factor is an important mediator of Notch signal transduction [2].

References

A two-step mechanism generates the spacing pattern of the ciliated cells in the skin of Xenopus embryos. Deblandre, G.A., Wettstein, D.A., Koyano-Nakagawa, N., Kintner, C. Development (1999) [Pubmed]
XSu(H)2 is an essential factor for gene expression and morphogenesis of the Xenopus gastrula embryo. Ito, M., Katada, T., Miyatani, S., Kinoshita, T. Int. J. Dev. Biol. (2007) [Pubmed]

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