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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

ANKHD1-EIF4EBP3  -  ANKHD1-EIF4EBP3 readthrough

Homo sapiens

Synonyms: MASK-BP3, MASK-BP3ARF
 
 
 
 
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High impact information on MASK-BP3

  • Interestingly, both eIF4E and MASK are downstream effectors of the Ras/MAPK pathway, which provides a rationale for the MASK-BP3 fusion in mammals [1].
  • Surprisingly, the open reading frame of the MASK-BP3 transcript is different from that of 4E-BP3, which indicates that exon B is translated using an alternative reading frame [1].

References

  1. Gene fusion and overlapping reading frames in the mammalian genes for 4E-BP3 and MASK. Poulin, F., Brueschke, A., Sonenberg, N. J. Biol. Chem. (2003) [Pubmed]
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