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Gene Review:

DIO2 - deiodinase, iodothyronine, type II

Sus scrofa

Murakami, M. et al.

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High impact information on DIO2

Thyrotropin receptors in brown adipose tissue: thyrotropin stimulates type II iodothyronine deiodinase and uncoupling protein-1 in brown adipocytes [1].

Anatomical context of DIO2

Type II iodothyronine deiodinase mRNA, its activity, and uncoupling protein-1 mRNA in cultured rat brown adipocytes were significantly increased by incubation with TSH in a dose-dependent manner [1].

References

Thyrotropin receptors in brown adipose tissue: thyrotropin stimulates type II iodothyronine deiodinase and uncoupling protein-1 in brown adipocytes. Murakami, M., Kamiya, Y., Morimura, T., Araki, O., Imamura, M., Ogiwara, T., Mizuma, H., Mori, M. Endocrinology (2001) [Pubmed]

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