Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

HCG15 - HLA complex group 15 (non-protein coding)

Homo sapiens

Synonyms: dJ25J6.6

Chen, C.D. et al., Martin, M.M. et al.

Martin, Martin,

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High impact information on HCG15

Patients with HCG15 < 150 mIU/ml but HCG22/HCG15 ratio > or = 15, still had a 90% chance of normal pregnancy [1].
In those with serum T < 50 ng/ dl our data suggest that a single injection of HCG 15 IU/kg, with serum T determined 48 hours later, is more discriminatory and offers the most reliable, easy to perform, least painful, and by far the most cost effective test to differentiate CDP from HH [2].

Analytical, diagnostic and therapeutic context of HCG15

We conclude that a single HCG15 determination combined with the ratio of HCG22 to HCG15 has a higher diagnostic accuracy for prediction of pregnancy outcome than either analysis alone [1].

References

Paired human chorionic gonadotrophin determinations for the prediction of pregnancy outcome in assisted reproduction. Chen, C.D., Ho, H.N., Wu, M.Y., Chao, K.H., Chen, S.U., Yang, Y.S. Hum. Reprod. (1997) [Pubmed]
Constitutional delayed puberty in males and hypogonadotropic hypogonadism: a reliable and cost-effective approach to differential diagnosis. Martin, M.M., Martin, A.L. Journal of pediatric endocrinology & metabolism : JPEM. (2005) [Pubmed]

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