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Gene Review

CycC  -  Cyclin C

Drosophila melanogaster

Synonyms: CG1C_DROME, CG7281, CLND, CYCC, Cln3, ...
 
 
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High impact information on CycC

  • Yeast cells rescued by a plasmid constitutively expressing this Drosophila cyclin C are unusually small, consistent with an unregulated high level of G1 cyclin function [1].
  • Unlike other cyclins identified in this complementation screen, there has been no evidence that cyclin C has a cell-cycle role in the cognate organism [2].

References

  1. An evolutionarily conserved cyclin homolog from Drosophila rescues yeast deficient in G1 cyclins. Léopold, P., O'Farrell, P.H. Cell (1991) [Pubmed]
  2. Drosophila Cdk8, a kinase partner of cyclin C that interacts with the large subunit of RNA polymerase II. Leclerc, V., Tassan, J.P., O'Farrell, P.H., Nigg, E.A., Léopold, P. Mol. Biol. Cell (1996) [Pubmed]
 
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