Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

Gyc-89Da - Guanylyl cyclase at 89Da

Drosophila melanogaster

Synonyms: CG14885, Dmel\CG14885, GYCb, Soluble guanylate cyclase 89Da

Morton, D.B. et al., Vermehren, A. et al.

Morton, Langlais, Stewart, Vermehren,

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High impact information on Gyc-89Da

By contrast, the Drosophila melanogaster atypical sGC subunits, Gyc-88E, Gyc-89Da and Gyc-89Db, are only slightly sensitive to NO, but are potently activated under hypoxic conditions [1].
The properties and distribution of Gyc-88E and Gyc-89Db have previously been described and here Gyc-89Da is described [2].

Regulatory relationships of Gyc-89Da

Gyc-89Da only forms an active guanylyl cyclase when co-expressed with Gyc-88E [2].

References

Oxygen-sensitive guanylyl cyclases in insects and their potential roles in oxygen detection and in feeding behaviors. Vermehren, A., Langlais, K.K., Morton, D.B. J. Insect Physiol. (2006) [Pubmed]
Comparison of the properties of the five soluble guanylyl cyclase subunits in Drosophila melanogaster. Morton, D.B., Langlais, K.K., Stewart, J.A., Vermehren, A. J. Insect Sci. (2005) [Pubmed]

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