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Gene Review

MID2  -  midline 2

Gallus gallus

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High impact information on MID2

  • The expression of cMid2 overlaps with that of cMid1 in the node, and we demonstrate that MID2 can both mimic MID1 function as a right side determinant and rescue the laterality defects caused by knocking down endogenous MID proteins in the node [1].


  1. Evidence of functional redundancy between MID proteins: implications for the presentation of Opitz syndrome. Granata, A., Savery, D., Hazan, J., Cheung, B.M., Lumsden, A., Quaderi, N.A. Dev. Biol. (2005) [Pubmed]
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