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PIK3CA  -  phosphatidylinositol-4,5-bisphosphate 3...

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High impact information on PIK3CA

  • The PIK3CA gene, coding for the catalytic subunit p110alpha of class IA phosphatidylinositol 3-kinases (PI3Ks), is frequently mutated in human cancer [1].


  1. Cancer-specific mutations in PIK3CA are oncogenic in vivo. Bader, A.G., Kang, S., Vogt, P.K. Proc. Natl. Acad. Sci. U.S.A. (2006) [Pubmed]
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