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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

E(spl)mgamma-HLH  -  Enhancer of split mgamma, helix-loop-helix

Drosophila melanogaster

Synonyms: CG8333, Dm-mB, Dmel\CG8333, E(Spl) HLH-m gamma, E(spl) m gamma, ...
 
 
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High impact information on HLHmgamma

  • This activity of E(spl)m7 and mgamma correlates with their ability to interact with proneural activators, through which they are probably tethered on target enhancers [1].
  • We also demonstrate that the characteristic inactivity of the E(spl)mgamma enhancer in the notum and margin territories of the wing disc can be overcome by elevated activity of the N receptor [2].

References

  1. Two modes of recruitment of E(spl) repressors onto target genes. Giagtzoglou, N., Alifragis, P., Koumbanakis, K.A., Delidakis, C. Development (2003) [Pubmed]
  2. Discrete enhancer elements mediate selective responsiveness of enhancer of split complex genes to common transcriptional activators. Nellesen, D.T., Lai, E.C., Posakony, J.W. Dev. Biol. (1999) [Pubmed]
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