Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

E(spl)m2-BFM - Enhancer of split m2, Bearded family member

Drosophila melanogaster

Synonyms: CG6104, DmelCG6104, Dmel\CG6104, E(Spl)m2, E(spl), ...

Lai, E.C. et al., Wurmbach, E. et al.

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High impact information on m2

We show that overexpression of either m2 or m6 interferes with N-dependent cell fate decisions in adult PNS development [1].
In this report, we analyze the structure, regulation and activity of the m1, m2 and m6 genes of the E(spl)-C [1].
Here we show that the E(spl)-C contains three additional Notch responsive, non-bHLH genes: m4 and ma are structurally related, whilst m2 encodes a novel protein [2].

References

The enhancer of split complex of Drosophila includes four Notch-regulated members of the bearded gene family. Lai, E.C., Bodner, R., Posakony, J.W. Development (2000) [Pubmed]
The Enhancer of split complex of Drosophila melanogaster harbors three classes of Notch responsive genes. Wurmbach, E., Wech, I., Preiss, A. Mech. Dev. (1999) [Pubmed]

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