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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

ALG11  -  ALG11, alpha-1,2-mannosyltransferase

Homo sapiens

Synonyms: Asparagine-linked glycosylation protein 11 homolog, CDG1P, GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase, GT8, Glycolipid 2-alpha-mannosyltransferase, ...
 
 
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High impact information on ALG11

  • Gene deletions point to certain genes, like alg11, as being essential yet revealed that others, such as the two versions of alg5, are not [1].
  • In vitro evidence for the dual function of Alg2 and Alg11: essential mannosyltransferases in N-linked glycoprotein biosynthesis [2].

References

  1. Protein N-glycosylation in Archaea: defining Haloferax volcanii genes involved in S-layer glycoprotein glycosylation. Abu-Qarn, M., Eichler, J. Mol. Microbiol. (2006) [Pubmed]
  2. In vitro evidence for the dual function of Alg2 and Alg11: essential mannosyltransferases in N-linked glycoprotein biosynthesis. O'Reilly, M.K., Zhang, G., Imperiali, B. Biochemistry (2006) [Pubmed]
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