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Chemical Compound Review

GLYCOPROTEIN     (2S)-2-acetamido-N'- [(3R,4R,5S,6R)-3...

Synonyms: CPD-8582, AC1L96W8, 2859-EP2270015A1, 2859-EP2284159A1, 2859-EP2287167A1, ...
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Disease relevance of GLYCOPROTEIN


Psychiatry related information on GLYCOPROTEIN


High impact information on GLYCOPROTEIN


Chemical compound and disease context of GLYCOPROTEIN


Biological context of GLYCOPROTEIN


Anatomical context of GLYCOPROTEIN


Associations of GLYCOPROTEIN with other chemical compounds

  • Induction of two transformation-sensitive membrane polypeptides in normal fibroblasts by a block in glycoprotein synthesis or glucose deprivation [31].
  • In some cases (Fc receptor, lysosomal glycoprotein Igp120), the determinant appears similar to that required for endocytosis via clathrin-coated pits; for Igp120, elimination of a single cytoplasmic domain tyrosine both blocks internalization and results in apical transport [32].
  • We establish that the position-specific antigen 2 (PS2), a Drosophila cell surface glycoprotein complex, is an invertebrate member of the vertebrate fibronectin receptor (integrin) family [33].
  • Here, we show that EXT1 is an ER-resident type II transmembrane glycoprotein whose expression in cells results in the alteration of the synthesis and display of cell surface heparan sulfate glycosaminoglycans (GAGs) [34].
  • The transport of sugar residues into the endoplasmic reticulum (ER) during glycoprotein synthesis was studied by examining the transmembrane orientations of the oligosaccharide-lipid precursors of asparagine-linked oligosaccharides [35].

Gene context of GLYCOPROTEIN


Analytical, diagnostic and therapeutic context of GLYCOPROTEIN


  1. The CD4-gp120 interaction and AIDS pathogenesis. Capon, D.J., Ward, R.H. Annu. Rev. Immunol. (1991) [Pubmed]
  2. The structure and function of the hemagglutinin membrane glycoprotein of influenza virus. Wiley, D.C., Skehel, J.J. Annu. Rev. Biochem. (1987) [Pubmed]
  3. Construction of a novel virus that targets HIV-1-infected cells and controls HIV-1 infection. Schnell, M.J., Johnson, J.E., Buonocore, L., Rose, J.K. Cell (1997) [Pubmed]
  4. Determinants for receptor interaction and cell killing on the avian retrovirus glycoprotein gp85. Dorner, A.J., Coffin, J.M. Cell (1986) [Pubmed]
  5. Sustained expression of genes delivered directly into liver and muscle by lentiviral vectors. Kafri, T., Blömer, U., Peterson, D.A., Gage, F.H., Verma, I.M. Nat. Genet. (1997) [Pubmed]
  6. Amyloid beta-protein deposition in tissues other than brain in Alzheimer's disease. Joachim, C.L., Mori, H., Selkoe, D.J. Nature (1989) [Pubmed]
  7. The HIV Env variant N283 enhances macrophage tropism and is associated with brain infection and dementia. Dunfee, R.L., Thomas, E.R., Gorry, P.R., Wang, J., Taylor, J., Kunstman, K., Wolinsky, S.M., Gabuzda, D. Proc. Natl. Acad. Sci. U.S.A. (2006) [Pubmed]
  8. Potent stimulation of monocytic endothelin-1 production by HIV-1 glycoprotein 120. Ehrenreich, H., Rieckmann, P., Sinowatz, F., Weih, K.A., Arthur, L.O., Goebel, F.D., Burd, P.R., Coligan, J.E., Clouse, K.A. J. Immunol. (1993) [Pubmed]
  9. Anti-idiotypic antibodies induce neutralizing antibodies to rabies virus glycoprotein. Reagan, K.J., Wunner, W.H., Wiktor, T.J., Koprowski, H. J. Virol. (1983) [Pubmed]
  10. Effect of electroconvulsive therapy on serum concentration of alpha-1-acid glycoprotein. DeVane, C.L., Lim, C., Carson, S.W., Tingle, D., Hackett, L., Ware, M.R. Biol. Psychiatry (1991) [Pubmed]
  11. Membrane cofactor protein (MCP or CD46): newest member of the regulators of complement activation gene cluster. Liszewski, M.K., Post, T.W., Atkinson, J.P. Annu. Rev. Immunol. (1991) [Pubmed]
  12. Lymphotoxin. Paul, N.L., Ruddle, N.H. Annu. Rev. Immunol. (1988) [Pubmed]
  13. Comparative aspects of glycoprotein structure. Kornfeld, R., Kornfeld, S. Annu. Rev. Biochem. (1976) [Pubmed]
  14. Mechanisms that regulate the function of the selectins and their ligands. Vestweber, D., Blanks, J.E. Physiol. Rev. (1999) [Pubmed]
  15. Control of acetylcholine receptors in skeletal muscle. Fambrough, D.M. Physiol. Rev. (1979) [Pubmed]
  16. Microheterogeneity among carbohydrate structures at the cell surface may be important in recognition phenomena. Stanley, P., Sudo, T. Cell (1981) [Pubmed]
  17. Effects of ursodeoxycholic acid and aspirin on the formation of lithogenic bile and gallstones during loss of weight. Broomfield, P.H., Chopra, R., Sheinbaum, R.C., Bonorris, G.G., Silverman, A., Schoenfield, L.J., Marks, J.W. N. Engl. J. Med. (1988) [Pubmed]
  18. A secreted glycoprotein induced by estrogen in human breast cancer cell lines. Westley, B., Rochefort, H. Cell (1980) [Pubmed]
  19. Pure alpha-secreting pituitary adenomas. Ridgway, E.C., Klibanski, A., Ladenson, P.W., Clemmons, D., Beitins, I.Z., McArthur, J.W., Martorana, M.A., Zervas, N.T. N. Engl. J. Med. (1981) [Pubmed]
  20. Altered C1 inhibitor genes in type I hereditary angioedema. Stoppa-Lyonnet, D., Tosi, M., Laurent, J., Sobel, A., Lagrue, G., Meo, T. N. Engl. J. Med. (1987) [Pubmed]
  21. Reduced temperature prevents transfer of a membrane glycoprotein to the cell surface but does not prevent terminal glycosylation. Matlin, K.S., Simons, K. Cell (1983) [Pubmed]
  22. An endothelial ligand for L-selectin is a novel mucin-like molecule. Lasky, L.A., Singer, M.S., Dowbenko, D., Imai, Y., Henzel, W.J., Grimley, C., Fennie, C., Gillett, N., Watson, S.R., Rosen, S.D. Cell (1992) [Pubmed]
  23. Competition for related but nonidentical binding sites on the glycoprotein IIb-IIIa complex by peptides derived from platelet adhesive proteins. Santoro, S.A., Lawing, W.J. Cell (1987) [Pubmed]
  24. The IIb-IIIa glycoprotein complex that mediates platelet aggregation is directly implicated in leukocyte adhesion. Burns, G.F., Cosgrove, L., Triglia, T., Beall, J.A., López, A.F., Werkmeister, J.A., Begley, C.G., Haddad, A.P., d'Apice, A.J., Vadas, M.A. Cell (1986) [Pubmed]
  25. Identification and isolation of a 140 kd cell surface glycoprotein with properties expected of a fibronectin receptor. Pytela, R., Pierschbacher, M.D., Ruoslahti, E. Cell (1985) [Pubmed]
  26. Structural characterization of the TAP molecule: a phosphatidylinositol-linked glycoprotein distinct from the T cell receptor/T3 complex and Thy-1. Reiser, H., Oettgen, H., Yeh, E.T., Terhorst, C., Low, M.G., Benacerraf, B., Rock, K.L. Cell (1986) [Pubmed]
  27. Properties of a basement membrane-related glycoprotein synthesized in culture by a mouse embryonal carcinoma-derived cell line. Chung, A.E., Jaffe, R., Freeman, I.L., Vergnes, J.P., Braginski, J.E., Carlin, B. Cell (1979) [Pubmed]
  28. Purified intercellular adhesion molecule-1 (ICAM-1) is a ligand for lymphocyte function-associated antigen 1 (LFA-1). Marlin, S.D., Springer, T.A. Cell (1987) [Pubmed]
  29. Expression of CD44 confers a new adhesive phenotype on transfected cells. St John, T., Meyer, J., Idzerda, R., Gallatin, W.M. Cell (1990) [Pubmed]
  30. Role of laminin A chain in the development of epithelial cell polarity. Klein, G., Langegger, M., Timpl, R., Ekblom, P. Cell (1988) [Pubmed]
  31. Induction of two transformation-sensitive membrane polypeptides in normal fibroblasts by a block in glycoprotein synthesis or glucose deprivation. Pouysségur, J., Shiu, R.P., Pastan, I. Cell (1977) [Pubmed]
  32. Basolateral sorting in MDCK cells requires a distinct cytoplasmic domain determinant. Hunziker, W., Harter, C., Matter, K., Mellman, I. Cell (1991) [Pubmed]
  33. The Drosophila PS2 antigen is an invertebrate integrin that, like the fibronectin receptor, becomes localized to muscle attachments. Bogaert, T., Brown, N., Wilcox, M. Cell (1987) [Pubmed]
  34. The putative tumour suppressor EXT1 alters the expression of cell-surface heparan sulfate. McCormick, C., Leduc, Y., Martindale, D., Mattison, K., Esford, L.E., Dyer, A.P., Tufaro, F. Nat. Genet. (1998) [Pubmed]
  35. Transmembrane movement of oligosaccharide-lipids during glycoprotein synthesis. Snider, M.D., Rogers, O.C. Cell (1984) [Pubmed]
  36. Biochemical studies of the human thymocyte cell-surface antigens T6, T9 and T10. Terhorst, C., van Agthoven, A., LeClair, K., Snow, P., Reinherz, E., Schlossman, S. Cell (1981) [Pubmed]
  37. Cardiac defects and renal failure in mice with targeted mutations in Pkd2. Wu, G., Markowitz, G.S., Li, L., D'Agati, V.D., Factor, S.M., Geng, L., Tibara, S., Tuchman, J., Cai, Y., Park, J.H., van Adelsberg, J., Hou, H., Kucherlapati, R., Edelmann, W., Somlo, S. Nat. Genet. (2000) [Pubmed]
  38. Drosophila substrate adhesion molecule: sequence of laminin B1 chain reveals domains of homology with mouse. Montell, D.J., Goodman, C.S. Cell (1988) [Pubmed]
  39. Essential function of Gli2 and Gli3 in the formation of lung, trachea and oesophagus. Motoyama, J., Liu, J., Mo, R., Ding, Q., Post, M., Hui, C.C. Nat. Genet. (1998) [Pubmed]
  40. Cloning and characterization of a new intercellular adhesion molecule ICAM-R. Vazeux, R., Hoffman, P.A., Tomita, J.K., Dickinson, E.S., Jasman, R.L., St John, T., Gallatin, W.M. Nature (1992) [Pubmed]
  41. Membrane receptors for murine leukemia viruses: characterization using the purified viral envelope glycoprotein, gp71. DeLarco, J., Todaro, G.J. Cell (1976) [Pubmed]
  42. Postcoital detection of a male-specific semen protein. Application to the investigation of rape. Graves, H.C., Sensabaugh, G.F., Blake, E.T. N. Engl. J. Med. (1985) [Pubmed]
  43. Human immunodeficiency virus type 2 infection associated with AIDS in West Africa. Clavel, F., Mansinho, K., Chamaret, S., Guetard, D., Favier, V., Nina, J., Santos-Ferreira, M.O., Champalimaud, J.L., Montagnier, L. N. Engl. J. Med. (1987) [Pubmed]
  44. Compartmentalized assembly of oligosaccharides on exported glycoproteins in yeast. Esmon, B., Novick, P., Schekman, R. Cell (1981) [Pubmed]
  45. The glycoprotein that is transported between successive compartments of the Golgi in a cell-free system resides in stacks of cisternae. Braell, W.A., Balch, W.E., Dobbertin, D.C., Rothman, J.E. Cell (1984) [Pubmed]
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