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LOC441453  -  similar to olfactory receptor, family 7,...

Homo sapiens

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High impact information on LOC441453

  • High expression of two of the tamoxifen-stimulated genes, YWHAZ/14-3-3z and LOC441453, was found to correlate significantly with disease recurrence following tamoxifen treatment in women with ER-positive cancers and hence seem to be markers of a poor prognosis [1].


  1. Gene expression preferentially regulated by tamoxifen in breast cancer cells and correlations with clinical outcome. Frasor, J., Chang, E.C., Komm, B., Lin, C.Y., Vega, V.B., Liu, E.T., Miller, L.D., Smeds, J., Bergh, J., Katzenellenbogen, B.S. Cancer Res. (2006) [Pubmed]
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