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Gene Review:

BMP6 - bone morphogenetic protein 6

Ovis aries

Juengel, J.L. et al., Pierre, A. et al.

Juengel, Reader, Bibby, Lun, Ross, Haydon, McNatty,

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High impact information on BMP6

BMP-6 action was only slightly reduced by both follistatin and noggin [1].
Furthermore, expression of BMP6 was limited to the oocyte of primordial as well as primary, pre-antral and antral follicles [2].

Analytical, diagnostic and therapeutic context of BMP6

As assessed by in situ hybridization, non-atretic ovine follicles expressed mRNA for BMP6 but not 2, 4 or 7 [2].

References

Testing the antagonistic effect of follistatin on BMP family members in ovine granulosa cells. Pierre, A., Pisselet, C., Monget, P., Monniaux, D., Fabre, S. Reprod. Nutr. Dev. (2005) [Pubmed]
The role of bone morphogenetic proteins 2, 4, 6 and 7 during ovarian follicular development in sheep: contrast to rat. Juengel, J.L., Reader, K.L., Bibby, A.H., Lun, S., Ross, I., Haydon, L.J., McNatty, K.P. Reproduction (2006) [Pubmed]

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