Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

MYH4 - myosin, heavy chain 4, skeletal muscle

Homo sapiens

Synonyms: MYH2B, MyHC-2B, MyHC-2b, MyHC-IIb, Myosin heavy chain 2b, ...

Tikunov, B. et al., Hilber, K. et al., Horton, M.J. et al.

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High impact information on MYH4

Therefore, in heart failure, myosin heavy chain I is increased (P < .0001) and myosin heavy chain IIb decreased from normal levels (P < .001) [1].
This holds also true for myosin heavy chain IIa, but human myosin heavy chain IIb is slower than rodent myosin heavy chain IIb [2].
Abundant expression of myosin heavy-chain IIB RNA in a subset of human masseter muscle fibres [3].

References

Chronic congestive heart failure elicits adaptations of endurance exercise in diaphragmatic muscle. Tikunov, B., Levine, S., Mancini, D. Circulation (1997) [Pubmed]
Kinetic properties of myosin heavy chain isoforms in single fibers from human skeletal muscle. Hilber, K., Galler, S., Gohlsch, B., Pette, D. FEBS Lett. (1999) [Pubmed]
Abundant expression of myosin heavy-chain IIB RNA in a subset of human masseter muscle fibres. Horton, M.J., Brandon, C.A., Morris, T.J., Braun, T.W., Yaw, K.M., Sciote, J.J. Arch. Oral Biol. (2001) [Pubmed]

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MYH4	Bos taurus
MYH4	Canis lupus familiaris
myhz1.1	Danio rerio
myhz1.2	Danio rerio
myha	Danio rerio
myhb	Danio rerio
myhc4	Danio rerio
myhz2	Danio rerio
ns:zf-e68	Danio rerio
wu:fd14a01	Danio rerio
zgc:66156	Danio rerio
MYH4	Macaca mulatta
Myh4	Mus musculus
MYH4	Pan troglodytes
Myh4	Rattus norvegicus
myh3	Xenopus (Silurana) tropicalis
LOC100492956	Xenopus (Silurana) tropicalis
myh7	Xenopus (Silurana) tropicalis
LOC100493121	Xenopus (Silurana) tropicalis

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