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Gene Review

sf1  -  splicing factor 1

Xenopus (Silurana) tropicalis

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High impact information on sf1

  • Since STAR/GSG proteins may regulate alternative splicing by competing with SF1 in the nucleus for specific branch-point sequences that signal intronic RNA, the formation of secondary structure in the QUA2 region in the unbound state of pXqua has important functional consequences [1].


  1. Solution structure and backbone dynamics of the KH-QUA2 region of the Xenopus STAR/GSG quaking protein. Maguire, M.L., Guler-Gane, G., Nietlispach, D., Raine, A.R., Zorn, A.M., Standart, N., Broadhurst, R.W. J. Mol. Biol. (2005) [Pubmed]
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