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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

PAFAH1B2  -  platelet-activating factor acetylhydrolase...

Homo sapiens

Synonyms: PAF acetylhydrolase 30 kDa subunit, PAF-AH 30 kDa subunit, PAF-AH subunit beta, PAFAH subunit beta, PAFAHB, ...
 
 
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High impact information on PAFAH1B2

  • Lis1 is a subunit of a brain platelet-activating factor acetylhydrolase (PAFAH1B) where it forms a heterotrimeric complex with two hydrolase subunits, referred to as 29 kDa (PAFAH1B3) and 30 kDa (PAFAH1B2) [1].
 

Biological context of PAFAH1B2

  • The beta and gamma subunits of the human platelet-activating factor acetyl hydrolase isoform Ib (PAFAH1B2 and PAFAH1B3) map to chromosome 11q23 and 19q13.1, respectively [2].

References

  1. Lissencephaly associated mutations suggest a requirement for the PAFAH1B heterotrimeric complex in brain development. Sweeney, K.J., Clark, G.D., Prokscha, A., Dobyns, W.B., Eichele, G. Mech. Dev. (2000) [Pubmed]
  2. The beta and gamma subunits of the human platelet-activating factor acetyl hydrolase isoform Ib (PAFAH1B2 and PAFAH1B3) map to chromosome 11q23 and 19q13.1, respectively. Moro, F., Arrigo, G., Fogli, A., Bernard, L., Carrozzo, R. Genomics (1998) [Pubmed]
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