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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

TAS2R3  -  taste receptor, type 2, member 3

Homo sapiens

Synonyms: T2R3, Taste receptor type 2 member 3
 
 
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High impact information on TAS2R3

  • The hT2R4 and hT2R5 contained four and one cSNPs that cause missense mutations, respectively, while hT2R3 included one silent nucleotide mutation [1].
  • Two single nucleotide polymorphisms were identified in the T2R3 gene, and associations between allele variants and AD in our population were not found [2].
  • Mutation screening of the genes SSBP and T2R3 located just centromeric to the breakpoint was performed in a set of 29 unrelated autistic sibling pairs who shared at least one chromosome 7 haplotype [2].
 

Biological context of TAS2R3

References

  1. Identification of coding single-nucleotide polymorphisms in human taste receptor genes involving bitter tasting. Ueda, T., Ugawa, S., Ishida, Y., Shibata, Y., Murakami, S., Shimada, S. Biochem. Biophys. Res. Commun. (2001) [Pubmed]
  2. A balanced reciprocal translocation t(5;7)(q14;q32) associated with autistic disorder: molecular analysis of the chromosome 7 breakpoint. Tentler, D., Brandberg, G., Betancur, C., Gillberg, C., Annerén, G., Orsmark, C., Green, E.D., Carlsson, B., Dahl, N. Am. J. Med. Genet. (2001) [Pubmed]
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