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Gene Review

CHIC1  -  cysteine-rich hydrophobic domain 1

Homo sapiens

Synonyms: BRX, Brain X-linked protein, Cysteine-rich hydrophobic domain-containing protein 1
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Disease relevance of CHIC1


High impact information on CHIC1

  • The importance of this domain for BRX activity in planta is underscored by our finding that expression of the C-terminal fragment of BRX, comprising the two BRX domains, is largely sufficient to rescue the brx phenotype [2].
  • BRX and BRXL1 similarity is most pronounced in a characteristic tandem repeat domain, which we named BRX domain [2].
  • BRX mediates feedback between brassinosteroid levels and auxin signalling in root growth [3].


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