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Gene Review:

gukh - GUK-holder

Drosophila melanogaster

Synonyms: CG14287, CG14288, CG31043, CG5456, CG6003, ...

Mathew, D. et al., Katoh, M. et al.

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High impact information on gukh

Recruitment of scribble to the synaptic scaffolding complex requires GUK-holder, a novel DLG binding protein [1].
Here, we searched for human homologs of Drosophila gukh by using bioinformatics, and identified GUKH1 and GUKH2 genes [2].

Anatomical context of gukh

RESULTS: Here we report the isolation of a new DLG-interacting protein, GUK-holder, that interacts with the GUK domain of DLG and which is dynamically expressed during synaptic bouton budding [1].

References

Recruitment of scribble to the synaptic scaffolding complex requires GUK-holder, a novel DLG binding protein. Mathew, D., Gramates, L.S., Packard, M., Thomas, U., Bilder, D., Perrimon, N., Gorczyca, M., Budnik, V. Curr. Biol. (2002) [Pubmed]
Identification and characterization of human GUKH2 gene in silico. Katoh, M., Katoh, M. Int. J. Oncol. (2004) [Pubmed]

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