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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Protein Binding

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Disease relevance of Protein Binding


Psychiatry related information on Protein Binding


High impact information on Protein Binding

  • The discovery in 1986 of a plasma protein termed LPS binding protein (LBP) led to the discovery of unanticipated mechanisms of LPS-induced cell activation [11].
  • Moreover, the Duffy antigen, which mediates invasion of erythrocytes by Plasmodium vivax, a major cause of malaria, is also a chemokine binding protein [12].
  • We review the unique properties of the IP3R that facilitate cell-type and stimulus-dependent control of function, with special emphasis on protein-binding partners [13].
  • These transcription factors coordinate the expression of genes involved in creating and maintaining the adipocyte phenotype including the insulin-responsive glucose transporter (GLUT4), stearoyl CoA desaturase 1 (SCD1), and the fatty acid binding protein (422/aP2) [14].
  • Ultraviolet light (UV)-damaged DNA binding protein (UV-DDB) is another complex that appears to be involved in the recognition of NER-inducing damage, although the precise role it plays and its relationship to XPC remain to be elucidated [15].

Chemical compound and disease context of Protein Binding


Biological context of Protein Binding


Anatomical context of Protein Binding


Associations of Protein Binding with chemical compounds


Gene context of Protein Binding


Analytical, diagnostic and therapeutic context of Protein Binding


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  2. Trans-activation by HIV-1 Tat via a heterologous RNA binding protein. Selby, M.J., Peterlin, B.M. Cell (1990) [Pubmed]
  3. A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-Abl tyrosine kinase in the cell cycle. Welch, P.J., Wang, J.Y. Cell (1993) [Pubmed]
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  20. Estrogen binding protein activity in Morris hepatoma 7777 compared with normal rat liver. Francavilla, A., Eagon, P.K., DiLeo, A., Van Thiel, D.H., Ove, P., Wu, S.K., Sax, S.A., Starzl, T.E. Gastroenterology (1984) [Pubmed]
  21. MyoD is a sequence-specific DNA binding protein requiring a region of myc homology to bind to the muscle creatine kinase enhancer. Lassar, A.B., Buskin, J.N., Lockshon, D., Davis, R.L., Apone, S., Hauschka, S.D., Weintraub, H. Cell (1989) [Pubmed]
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  23. Molecular interactions within the ecdysone regulatory hierarchy: DNA binding properties of the Drosophila ecdysone-inducible E74A protein. Urness, L.D., Thummel, C.S. Cell (1990) [Pubmed]
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  30. Immunophilins mediate the neuroprotective effects of FK506 in focal cerebral ischaemia. Sharkey, J., Butcher, S.P. Nature (1994) [Pubmed]
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