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Gene Review

Cacng4  -  calcium channel, voltage-dependent, gamma...

Mus musculus

Synonyms: AI413107, AW491861, Neuronal voltage-gated calcium channel gamma-4 subunit, TARP gamma-4, Transmembrane AMPAR regulatory protein gamma-4, ...
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Disease relevance of Cacng4

  • The homozygous Cacng4-targeted mutant mouse appeared normal with no ataxic gait or absence seizures, suggesting that other members of the gamma subunit family might functionally compensate for the absence of CACNG4 [1].

High impact information on Cacng4


Other interactions of Cacng4

  • To test this hypothesis, the targeted Cacng4 mutation was combined with alleles of Cacng2 [1].


  1. A targeted mutation in Cacng4 exacerbates spike-wave seizures in stargazer (Cacng2) mice. Letts, V.A., Mahaffey, C.L., Beyer, B., Frankel, W.N. Proc. Natl. Acad. Sci. U.S.A. (2005) [Pubmed]
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