Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

Cacng4 - calcium channel, voltage-dependent, gamma...

Mus musculus

Synonyms: AI413107, AW491861, Neuronal voltage-gated calcium channel gamma-4 subunit, TARP gamma-4, Transmembrane AMPAR regulatory protein gamma-4, ...

Letts, V.A. et al.

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Disease relevance of Cacng4

The homozygous Cacng4-targeted mutant mouse appeared normal with no ataxic gait or absence seizures, suggesting that other members of the gamma subunit family might functionally compensate for the absence of CACNG4 [1].

High impact information on Cacng4

A targeted mutation in Cacng4 exacerbates spike-wave seizures in stargazer (Cacng2) mice [1].

Other interactions of Cacng4

To test this hypothesis, the targeted Cacng4 mutation was combined with alleles of Cacng2 [1].

References

A targeted mutation in Cacng4 exacerbates spike-wave seizures in stargazer (Cacng2) mice. Letts, V.A., Mahaffey, C.L., Beyer, B., Frankel, W.N. Proc. Natl. Acad. Sci. U.S.A. (2005) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

CACNG4	Bos taurus
CACNG4	Canis lupus familiaris
cacng4b	Danio rerio
LOC100859571	Gallus gallus
CACNG4	Gallus gallus
CACNG4	Homo sapiens
CACNG4	Pan troglodytes
Cacng4	Rattus norvegicus
LOC100486554	Xenopus (Silurana) tropicalis

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