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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

RIN2  -  Ras and Rab interactor 2

Homo sapiens

Synonyms: MACS, RASSF4, Ras association domain family 4, Ras inhibitor JC265, Ras interaction/interference protein 2
 
 
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High impact information on RIN2

  • We then studied whether RIN2 was involved in the HGF-induced endocytosis of E-cadherin in intact Madin-Darby canine kidney cells [1].
  • RIN3 displays the same biochemical properties as RIN2, the stimulator and stabilizer of GTP-Rab5 [2].

References

  1. Involvement of the Ras-Ras-activated Rab5 guanine nucleotide exchange factor RIN2-Rab5 pathway in the hepatocyte growth factor-induced endocytosis of E-cadherin. Kimura, T., Sakisaka, T., Baba, T., Yamada, T., Takai, Y. J. Biol. Chem. (2006) [Pubmed]
  2. RIN3: a novel Rab5 GEF interacting with amphiphysin II involved in the early endocytic pathway. Kajiho, H., Saito, K., Tsujita, K., Kontani, K., Araki, Y., Kurosu, H., Katada, T. J. Cell. Sci. (2003) [Pubmed]
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