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Gene Review

SDAD1  -  SDA1 domain containing 1

Homo sapiens

Synonyms: FLJ10498, NUC130, Nucleolar protein 130, Protein SDA1 homolog, SDA1 domain-containing protein 1, ...
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High impact information on SDAD1

  • CONCLUSION: Our results suggests that genetic variations in a haplotype block spanning the SDA1 domain containing 1 and CXC chemokine genes on 4q21 may contribute to development of SAR in the Japanese population [1].
  • We confirmed that the interacting proteins, PUM2 and DAZL, are capable of binding the same RNA target and further characterized mRNA sequences bound by both proteins in the 3'UTR of human SDAD1 mRNA [2].


  1. Association of a haplotype block spanning SDAD1 gene and CXC chemokine genes with allergic rhinitis. Zhang, J., Noguchi, E., Migita, O., Yokouchi, Y., Nakayama, J., Shibasaki, M., Arinami, T. J. Allergy Clin. Immunol. (2005) [Pubmed]
  2. Identification and characterization of RNA sequences to which human PUMILIO-2 (PUM2) and deleted in Azoospermia-like (DAZL) bind. Fox, M., Urano, J., Reijo Pera, R.A. Genomics (2005) [Pubmed]
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