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Gene Review

PPP2R2A  -  protein phosphatase 2, regulatory subunit...

Homo sapiens

Synonyms: B55A, B55ALPHA, PP2A subunit B isoform B55-alpha, PP2A subunit B isoform PR55-alpha, PP2A subunit B isoform R2-alpha, ...
 
 
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High impact information on PPP2R2A

  • Our findings suggest that deregulation of CHEK2 and/or PPP2R2A is of pathogenetic importance in at least a subset of germ cell tumors [1].
 

Analytical, diagnostic and therapeutic context of PPP2R2A

  • Fluorescence in situ hybridization and reverse transcription-polymerase chain reaction disclosed that t(8;22) resulted in the fusion of the genes PPP2R2A and CHEK2, with an inserted fragment belonging to class I endogenous retrovirus-related sequences at the junction [1].

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