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Gene Review

PLEKHG6  -  pleckstrin homology domain containing,...

Homo sapiens

Synonyms: FLJ10665, MYOGEF, MyoGEF, Myosin-interacting guanine nucleotide exchange factor, PH domain-containing family G member 6, ...
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Regulatory relationships of PLEKHG6

  • Our results suggest that Plk1 can regulate MyoGEF activity and localization, contributing to the regulation of cytokinesis [1].


  1. Phosphorylation of MyoGEF on Thr-574 by Plk1 promotes MyoGEF localization to the central spindle. Asiedu, M., Wu, D., Matsumura, F., Wei, Q. J. Biol. Chem. (2008) [Pubmed]
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