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Gene Review

NEIL3  -  nei endonuclease VIII-like 3 (E. coli)

Homo sapiens

Synonyms: DNA glycosylase FPG2, DNA glycosylase/AP lyase Neil3, Endonuclease 8-like 3, Endonuclease VIII-like 3, FGP2, ...
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Disease relevance of NEIL3


Biological context of NEIL3


  1. DNA glycosylase activities for thymine residues oxidized in the methyl group are functions of the hNEIL1 and hNTH1 enzymes in human cells. Zhang, Q.M., Yonekura, S., Takao, M., Yasui, A., Sugiyama, H., Yonei, S. DNA Repair (Amst.) (2005) [Pubmed]
  2. The novel DNA glycosylase, NEIL1, protects mammalian cells from radiation-mediated cell death. Rosenquist, T.A., Zaika, E., Fernandes, A.S., Zharkov, D.O., Miller, H., Grollman, A.P. DNA Repair (Amst.) (2003) [Pubmed]
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