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Gene Review

NXF3  -  nuclear RNA export factor 3

Homo sapiens

Synonyms: Nuclear RNA export factor 3, TAP-like protein 3, TAPL-3, TAPL3
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High impact information on NXF3

  • NXF3-dependent RNA export is therefore blocked by Crm1-specific inhibitors that do not affect TAP function [1].
  • Here we demonstrate that NXF3, a human RNA binding protein related to TAP, lacks this domain yet retains the ability to export tethered RNA transcripts and to shuttle between the nucleus and the cytoplasm [1].

Biological context of NXF3


  1. Two closely related human nuclear export factors utilize entirely distinct export pathways. Yang, J., Bogerd, H.P., Wang, P.J., Page, D.C., Cullen, B.R. Mol. Cell (2001) [Pubmed]
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