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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

NXF3  -  nuclear RNA export factor 3

Homo sapiens

Synonyms: Nuclear RNA export factor 3, TAP-like protein 3, TAPL-3, TAPL3
 
 
 
 
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High impact information on NXF3

  • NXF3-dependent RNA export is therefore blocked by Crm1-specific inhibitors that do not affect TAP function [1].
  • Here we demonstrate that NXF3, a human RNA binding protein related to TAP, lacks this domain yet retains the ability to export tethered RNA transcripts and to shuttle between the nucleus and the cytoplasm [1].
 

Biological context of NXF3

References

  1. Two closely related human nuclear export factors utilize entirely distinct export pathways. Yang, J., Bogerd, H.P., Wang, P.J., Page, D.C., Cullen, B.R. Mol. Cell (2001) [Pubmed]
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