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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

SCAF4  -  SR-related CTD-associated factor 4

Homo sapiens

Synonyms: CTD-binding SR-like protein RA4, DKFZp434E098, KIAA1172, SFRS15, SR-related and CTD-associated factor 4, ...
 
 
 
 
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High impact information on SFRS15

  • The truncated p63 failed to associate with the C-terminal domain of RNA polymerase II through SRA4 protein and, therefore affected keratinocyte proliferation, differentiation and survival and may strongly contribute to AEC phenotype [1].

References

  1. AEC-associated p63 mutations lead to alternative splicing/protein stabilization of p63 and modulation of Notch signaling. Huang, Y.P., Kim, Y., Li, Z., Fomenkov, T., Fomenkov, A., Ratovitski, E.A. Cell Cycle (2005) [Pubmed]
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