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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

G6PC2  -  glucose-6-phosphatase, catalytic, 2

Homo sapiens

Synonyms: G-6-Pase 2, G6Pase 2, Glucose-6-phosphatase 2, IGRP, Islet-specific glucose-6-phosphatase catalytic subunit-related protein
 
 
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High impact information on G6PC2

  • RESULTS: Alternative splicing results in differential expression of G6PC2 transcripts in thymus and spleen compared with pancreas [1].
  • However, islet-specific G6Pase catalytic subunit-related protein (IGRP, G6PC2) was expressed in a tissue-specific manner, and was detectable only in hypothalamus tissue at increased template inputs [2].

References

  1. Alternative splicing of G6PC2, the gene coding for the islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP), results in differential expression in human thymus and spleen compared with pancreas. Dogra, R.S., Vaidyanathan, P., Prabakar, K.R., Marshall, K.E., Hutton, J.C., Pugliese, A. Diabetologia (2006) [Pubmed]
  2. Expression of glucose-6-phosphatase system genes in murine cortex and hypothalamus. Goh, B.H., Khan, A., Efendić, S., Portwood, N. Horm. Metab. Res. (2006) [Pubmed]
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