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Gene Review:

KLKP1 - kallikrein pseudogene 1

Homo sapiens

Synonyms: KARMA, KLK31P, KRSP1, Kallikrein-related in prostate protein 1, Kallikrein-related mRNA protein, ...

Lu, W. et al.

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Disease relevance of KLKP1

KLK31P is expressed at lower levels in localized and metastatic prostate cancer cells than in normal prostate cells [1].

High impact information on KLKP1

KLK31P is a novel androgen regulated and transcribed pseudogene of kallikreins that is expressed at lower levels in prostate cancer cells than in normal prostate cells [1].
CONCLUSIONS: KLK31P is a novel androgen regulated and transcribed pseudogene of kallikreins that may play a role in prostate carcinogenesis or maintenance [1].

Biological context of KLKP1

RESULTS: We have characterized this gene, named as KLK31P by the HUGO Gene Nomenclature Committee, as an unprocessed KLK pseudogene [1].

Associations of KLKP1 with chemical compounds

KLK31P is expressed abundantly in prostate tissues and is androgen regulated [1].

References

KLK31P is a novel androgen regulated and transcribed pseudogene of kallikreins that is expressed at lower levels in prostate cancer cells than in normal prostate cells. Lu, W., Zhou, D., Glusman, G., Utleg, A.G., White, J.T., Nelson, P.S., Vasicek, T.J., Hood, L., Lin, B. Prostate (2006) [Pubmed]

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