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Gene Review

RPS24  -  ribosomal protein S24

Homo sapiens

Synonyms: 40S ribosomal protein S24, DBA3, S24
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Disease relevance of RPS24


High impact information on RPS24

  • Mapping of the human ribosomal small subunit protein gene RPS24 to the chromosome 10q22-q23 boundary [2].
  • The nucleotide sequence of human RPS24 (4942 bp), its exon-intron organization and mRNA transcription start point were determined using standard procedures [3].
  • Starting with a cloned cDNA encoding human ribosomal protein S24 [Brown et al., Gene 91 (1990) 293-296], we PCR-amplified two introns from the human RPS24 locus [3].
  • Three of them, SelM, elF-4AI, and RPS24, seemed to be linked to a global change in cellular metabolism and cell growth [4].


  1. Ribosomal protein S24 gene is mutated in Diamond-Blackfan anemia. Gazda, H.T., Grabowska, A., Merida-Long, L.B., Latawiec, E., Schneider, H.E., Lipton, J.M., Vlachos, A., Atsidaftos, E., Ball, S.E., Orfali, K.A., Niewiadomska, E., Da Costa, L., Tchernia, G., Niemeyer, C., Meerpohl, J.J., Stahl, J., Schratt, G., Glader, B., Backer, K., Wong, C., Nathan, D.G., Beggs, A.H., Sieff, C.A. Am. J. Hum. Genet. (2006) [Pubmed]
  2. Mapping of the human ribosomal small subunit protein gene RPS24 to the chromosome 10q22-q23 boundary. Jones, A.M., Marzella, R., Rocchi, M., Hewitt, J.E. Genomics (1997) [Pubmed]
  3. The gene encoding human ribosomal protein S24 and tissue-specific expression of differentially spliced mRNAs. Xu, W.B., Roufa, D.J. Gene (1996) [Pubmed]
  4. Identification of CBFA1-regulated genes on SaOs-2 cells. Bertaux, K., Broux, O., Chauveau, C., Jeanfils, J., Devedjian, J.C. J. Bone Miner. Metab. (2005) [Pubmed]
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