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Gene Review

Pttg1  -  pituitary tumor-transforming 1

Rattus norvegicus

Synonyms: Pituitary tumor-transforming gene 1 protein, Pttg, Securin
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Disease relevance of Pttg1

  • BACKGROUND: Pituitary tumor transforming gene (PTTG), homologous to a mammalian securin, plays a pivotal role in cell transformation, however, its biological function(s) in normal tissues is not fully understood [1].


  1. A novel molecular marker of pituitary tumor transforming gene involves in a rat liver regeneration. Akino, K., Akita, S., Mizuguchi, T., Takumi, I., Yu, R., Wang, X.Y., Rozga, J., Demetriou, A.A., Melmed, S., Ohtsuru, A., Yamashita, S. J. Surg. Res. (2005) [Pubmed]
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