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DNAJC1  -  DnaJ (Hsp40) homolog, subfamily C, member 1

Homo sapiens

Synonyms: DNAJL1, DnaJ homolog subfamily C member 1, DnaJ protein homolog MTJ1, ERdj1, HTJ1, ...
 
 
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High impact information on DNAJC1

  • Here we describe the cloning of the human homologue HTJ1 and its interaction with alpha(1)-antichymotrypsin (ACT), a member of the serine proteinase inhibitor (serpin) family [1].
  • Here, we identified a new variant of human inter-alpha-trypsin inhibitor heavy chain 4 (ITIH4) that also interacts with the SANT2 domain of HTJ1 [2].

References

  1. The SANT2 domain of the murine tumor cell DnaJ-like protein 1 human homologue interacts with alpha1-antichymotrypsin and kinetically interferes with its serpin inhibitory activity. Kroczynska, B., Evangelista, C.M., Samant, S.S., Elguindi, E.C., Blond, S.Y. J. Biol. Chem. (2004) [Pubmed]
  2. BIP co-chaperone MTJ1/ERDJ1 interacts with inter-alpha-trypsin inhibitor heavy chain 4. Kroczynska, B., King-Simmons, L., Alloza, L., Alava, M.A., Elguindi, E.C., Blond, S.Y. Biochem. Biophys. Res. Commun. (2005) [Pubmed]
 
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