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Gene Review:

TNFAIP2 - tumor necrosis factor, alpha-induced...

Homo sapiens

Synonyms: B94, EXOC3L3, Primary response gene B94 protein, TNF alpha-induced protein 2, Tumor necrosis factor alpha-induced protein 2

Rusiniak, M.E. et al., Einstein, M.H. et al.

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High impact information on TNFAIP2

Identification of B94 (TNFAIP2) as a potential retinoic acid target gene in acute promyelocytic leukemia [1].
The B94 gene (TNFAIP2; Unigene Hs.101382), originally identified as a tumor necrosis factor alpha-inducible gene in endothelial cells, was one of several genes found to be induced by RA specifically in TF1-PR cells, but not in TF1-neo (control) cells [1].
Utilization of the human genome sequence localizes human papillomavirus type 16 DNA integrated into the TNFAIP2 gene in a fatal cervical cancer from a 39-year-old woman [2].
Search of the draft human genome sequence confirmed the chromosomal location and revealed a disruption of the TNFAIP2 cytokine/retinoic acid-inducible gene [2].

References

Identification of B94 (TNFAIP2) as a potential retinoic acid target gene in acute promyelocytic leukemia. Rusiniak, M.E., Yu, M., Ross, D.T., Tolhurst, E.C., Slack, J.L. Cancer Res. (2000) [Pubmed]
Utilization of the human genome sequence localizes human papillomavirus type 16 DNA integrated into the TNFAIP2 gene in a fatal cervical cancer from a 39-year-old woman. Einstein, M.H., Cruz, Y., El-Awady, M.K., Popescu, N.C., DiPaolo, J.A., van Ranst, M., Kadish, A.S., Romney, S., Runowicz, C.D., Burk, R.D. Clin. Cancer Res. (2002) [Pubmed]

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