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Gene Review

Cnfn  -  cornifelin

Mus musculus

Synonyms: 2210418J09Rik, Cornifelin
 
 
 
 
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High impact information on Cnfn

  • Human cornifelin contains 112 amino acids and is expressed in the uterus, cervix, and skin [1].
  • Using these mice, we have shown that cornifelin is directly or indirectly cross-linked to at least two other cornified envelope proteins, loricrin and involucrin, in vivo [1].
 

Analytical, diagnostic and therapeutic context of Cnfn

  • In situ hybridization analysis demonstrated the presence of human cornifelin in the granular cell layer of the epidermis [1].

References

  1. Identification and characterization of a novel component of the cornified envelope, cornifelin. Michibata, H., Chiba, H., Wakimoto, K., Seishima, M., Kawasaki, S., Okubo, K., Mitsui, H., Torii, H., Imai, Y. Biochem. Biophys. Res. Commun. (2004) [Pubmed]
 
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