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Gene Review

IL1R2  -  interleukin 1 receptor, type II

Homo sapiens

Synonyms: CD121 antigen-like family member B, CD121b, CDw121b, IL-1 type II receptor, IL-1R-2, ...
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High impact information on IL1R2

  • In the presence of ionomycin, overexpression of UBD in T(h) cells leads to the induction of IL1R2 that resemble FOXP3-transduced T(h) cells and naturally derived T(reg) cells [1].


  1. UBD, a downstream element of FOXP3, allows the identification of LGALS3, a new marker of human regulatory T cells. Ocklenburg, F., Moharregh-Khiabani, D., Geffers, R., Janke, V., Pfoertner, S., Garritsen, H., Groebe, L., Klempnauer, J., Dittmar, K.E., Weiss, S., Buer, J., Probst-Kepper, M. Lab. Invest. (2006) [Pubmed]
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