Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

IRX3 - iroquois homeobox 3

Homo sapiens

Synonyms: Homeodomain protein IRXB1, IRX-1, IRXB1, Iroquois homeobox protein 3, Iroquois-class homeodomain protein IRX-3

Ordway, J.M. et al.

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High impact information on IRX3

Uniquely, hypermethylation of the CGI within an IRX3 exon was correlated with over-expression of IRX3 in tumor tissues and cell lines relative to normal brain samples [1].

References

Comprehensive DNA methylation profiling in a human cancer genome identifies novel epigenetic targets. Ordway, J.M., Bedell, J.A., Citek, R.W., Nunberg, A., Garrido, A., Kendall, R., Stevens, J.R., Cao, D., Doerge, R.W., Korshunova, Y., Holemon, H., McPherson, J.D., Lakey, N., Leon, J., Martienssen, R.A., Jeddeloh, J.A. Carcinogenesis (2006) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

IRX3	Bos taurus
IRX3	Canis lupus familiaris
Irx3	Mus musculus
IRX3	Pan troglodytes

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