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Abca2  -  ATP-binding cassette, subfamily A (ABC1),...

Rattus norvegicus

Synonyms: ATP-binding cassette 2, ATP-binding cassette sub-family A member 2, ATP-binding cassette transporter 2, Abc2
 
 
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Disease relevance of Abca2

  • We recently cloned a full-length cDNA of the rat ATP-binding cassette transporter 2 (ABC2, or ABCA2) protein, a member of the ABC1 (or ABCA) subfamily (-ABC1/ABCA1 is a causal gene for Tangier disease) and found it to be strongly expressed in the rat brain [1].
 

High impact information on Abca2

  • ATP-binding cassette transporter ABCA2 (ABC2) expression in the developing spinal cord and PNS during myelination [2].
  • We examined developmental characteristics of the ATP-binding cassette transporter ABCA2 (or ABC2) -expressing cells in rat spinal cord and peripheral nerves [2].

References

  1. Atp-binding cassette transporter ABC2/ABCA2 in the rat brain: a novel mammalian lysosome-associated membrane protein and a specific marker for oligodendrocytes but not for myelin sheaths. Zhou, C., Zhao, L., Inagaki, N., Guan, J., Nakajo, S., Hirabayashi, T., Kikuyama, S., Shioda, S. J. Neurosci. (2001) [Pubmed]
  2. ATP-binding cassette transporter ABCA2 (ABC2) expression in the developing spinal cord and PNS during myelination. Zhou, C.J., Inagaki, N., Pleasure, S.J., Zhao, L.X., Kikuyama, S., Shioda, S. J. Comp. Neurol. (2002) [Pubmed]
 
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