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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

LY6G6C  -  lymphocyte antigen 6 complex, locus G6C

Homo sapiens

Synonyms: C6orf24, G6C, G6c, Lymphocyte antigen 6 complex locus protein G6c, NG24, ...
 
 
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High impact information on LY6G6C

  • Three of them (G6C, G6D, and G6E) encode putative proteins that belong to the Ly-6 superfamily, known to be GPI-anchored proteins attached to the cell surface [1].
  • For Ly-6H, GML and G6C, no or very low expression was observed in keratinocytes and HNSCC [2].

References

  1. Genes encoding three new members of the leukocyte antigen 6 superfamily and a novel member of Ig superfamily, together with genes encoding the regulatory nuclear chloride ion channel protein (hRNCC) and an N omega-N omega-dimethylarginine dimethylaminohydrolase homologue, are found in a 30-kb segment of the MHC class III region. Ribas, G., Neville, M., Wixon, J.L., Cheng, J., Campbell, R.D. J. Immunol. (1999) [Pubmed]
  2. Characterization of the human Ly-6 antigens, the newly annotated member Ly-6K included, as molecular markers for head-and-neck squamous cell carcinoma. de Nooij-van Dalen, A.G., van Dongen, G.A., Smeets, S.J., Nieuwenhuis, E.J., Stigter-van Walsum, M., Snow, G.B., Brakenhoff, R.H. Int. J. Cancer (2003) [Pubmed]
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