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Gene Review:

ALS3 - protein aluminum sensitive 3

Arabidopsis thaliana

Synonyms: ALUMINUM SENSITIVE 3, F3G5.12, F3G5_12

Larsen, P.B. et al.

Larsen, Geisler, Jones, Williams, Cancel,

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High impact information on ALS3

From our results, it appears that ALS3 encodes an ABC transporter-like protein that is required for Al resistance/tolerance and may function to redistribute accumulated Al away from sensitive tissues in order to protect the growing root from the toxic effects of Al [1].
Immunolocalization indicates that ALS3 predominantly accumulates in the plasma membrane of cells that express ALS3 [1].

Analytical, diagnostic and therapeutic context of ALS3

Based on GUS fusion and in situ hybridization analyses, ALS3 is primarily expressed in leaf hydathodes and the phloem throughout the plant, along with the root cortex following Al treatment [1].

References

ALS3 encodes a phloem-localized ABC transporter-like protein that is required for aluminum tolerance in Arabidopsis. Larsen, P.B., Geisler, M.J., Jones, C.A., Williams, K.M., Cancel, J.D. Plant J. (2005) [Pubmed]

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