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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

HR3  -  RPW8-like protein 3

Arabidopsis thaliana

Synonyms: INTRACELLULAR MILDEW A 10, MLA10, homolog of RPW8 3
 
 
 
 
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High impact information on HR3

  • The A. lyrata locus contains four genes orthologous to HR1, HR2, HR3, and RPW8.2, respectively [1].
 

Analytical, diagnostic and therapeutic context of HR3

  • Sequence analyses suggested that the RPW8 gene family in Brassicaceae originated from an HR3-like ancestor gene through a series of duplications and that RPW8.1 and RPW8.2 evolved from functional diversification through positive selection several MYA [1].

References

  1. Origin and maintenance of a broad-spectrum disease resistance locus in Arabidopsis. Xiao, S., Emerson, B., Ratanasut, K., Patrick, E., O'Neill, C., Bancroft, I., Turner, J.G. Mol. Biol. Evol. (2004) [Pubmed]
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