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Gene Review

Celsr3  -  cadherin, EGF LAG seven-pass G-type...

Rattus norvegicus

Synonyms: Cadherin EGF LAG seven-pass G-type receptor 3, Megf2, Multiple EGF-like domains protein 2, Multiple epidermal growth factor-like domains protein 2
 
 
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High impact information on Celsr3

  • Together, the high-density microarray data not only begin to suggest how separate genetic programs in the UB and MM orchestrate the formation of the whole kidney, but also suggest the involvement of heretofore largely unexplored developmental pathways (involving HNF-6, ADAM-10, Celsr-3, DDR2, and other genes) in nephrogenesis [1].
  • Celsr-3, a protein, which along with members of the Wnt-frizzled transduction cascade, might be involved in the polarization of the forming nephron, was found to be highly expressed in differentiating MM [1].
  • Celsr3 localized to punctate structures in the adluminal epithelium from postnatal day 40, consistent with elongate spermatid expression [2].

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