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Gene Review

IVY1  -  Ivy1p

Saccharomyces cerevisiae S288c

Synonyms: Interaction with VPS33 and YPT7 protein 1, Protein IVY1, YD9934.14, YDR229W
 
 
 
 
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High impact information on IVY1

  • All effects caused by the overexpression of Ivy1p can be reset by simultaneously raising the amount of Vps33p [1].
  • While deletion of IVY1 does not lead to any recognized change in phenotype, overexpression of Ivy1p leads to fragmentation of the vacuole, missorting of the vacuolar enzyme carboxypeptidase Y (CPY) to the exterior of the cell, and an accumulation of multivesicular bodies inside the cell [1].
 

Anatomical context of IVY1

  • The intracellular level of Ivy1p increases in cells approaching stationary growth phase at which part of the protein is located at the rim of the vacuole [1].

References

 
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