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Gene Review

HIR3  -  Hir3p

Saccharomyces cerevisiae S288c

Synonyms: HPC1, Histone transcription regulator 3, J2161, YJR140C
 
 
 
 
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High impact information on HIR3

  • The fortuitous presence of a mutation in the CAC3 gene in the strain in which this screen was undertaken enabled us to discover that double mutaions of cac3 and hir3, but neither of the two single mutations, caused a dramatic increase in the rate of retrotransposition [1].

References

  1. Yeast Ty1 retrotransposition is stimulated by a synergistic interaction between mutations in chromatin assembly factor I and histone regulatory proteins. Qian, Z., Huang, H., Hong, J.Y., Burck, C.L., Johnston, S.D., Berman, J., Carol, A., Liebman, S.W. Mol. Cell. Biol. (1998) [Pubmed]
 
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