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Gene Review

CTR9  -  Ctr9p

Saccharomyces cerevisiae S288c

Synonyms: CDP1, Centromere-binding factor 1-dependent protein 1, Cln three-requiring protein 9, RNA polymerase-associated protein CTR9, YOL145C
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High impact information on CTR9

  • Deletion of either PAF1 or CTR9 leads to similar severe pleiotropic phenotypes, which are unaltered when the two mutations are combined [1].
  • Paf1p and Cdc73p were previously reported to be RNA poly-merase II-associated proteins, suggesting that the Ctr9p complex may interact with the general transcription apparatus [2].


  1. Ctr9, Rtf1, and Leo1 are components of the Paf1/RNA polymerase II complex. Mueller, C.L., Jaehning, J.A. Mol. Cell. Biol. (2002) [Pubmed]
  2. A role for Ctr9p and Paf1p in the regulation G1 cyclin expression in yeast. Koch, C., Wollmann, P., Dahl, M., Lottspeich, F. Nucleic Acids Res. (1999) [Pubmed]
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