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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

HOR7  -  Hor7p

Saccharomyces cerevisiae S288c

Synonyms: Protein A0.5, Protein HOR7, YMR251BW, YMR251W-A
 
 
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High impact information on HOR7

  • HOR7 belongs to a group of hyperosmolarity-responsive genes and encodes a small (59-residue) type I membrane protein that localizes at the plasma membrane [1].
  • Here we report the isolation of HOR7 as a multicopy suppressor of the Ca(2+)-sensitive phenotype of Deltacsg1Deltacsh1 cells [1].
  • Hor7p is not required for high Ca(2+) or Na(+) tolerance [1].
  • HOR2 and HOR7 corresponded to novel genes [2].
 

Associations of HOR7 with chemical compounds

  • Instead, we find that Hor7p-overproducing cells display an increased resistance to high salt, sensitivity to low pH, and a reduced uptake of methylammonium, an indicator of the plasma membrane potential [1].

References

  1. HOR7, a multicopy suppressor of the Ca2+-induced growth defect in sphingolipid mannosyltransferase-deficient yeast. Lisman, Q., Urli-Stam, D., Holthuis, J.C. J. Biol. Chem. (2004) [Pubmed]
  2. Cloning and characterization of seven cDNAs for hyperosmolarity-responsive (HOR) genes of Saccharomyces cerevisiae. Hirayama, T., Maeda, T., Saito, H., Shinozaki, K. Mol. Gen. Genet. (1995) [Pubmed]
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