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Gene Review

HOS3  -  Hos3p

Saccharomyces cerevisiae S288c

Synonyms: Histone deacetylase HOS3, LPH11W, YPL116W
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High impact information on HOS3

  • We propose that while factors that interact with HOS3 may sequester the catalytic subunit at specific cellular sites, they are not required for HOS3 histone deacetylase activity [1].


  1. Yeast HOS3 forms a novel trichostatin A-insensitive homodimer with intrinsic histone deacetylase activity. Carmen, A.A., Griffin, P.R., Calaycay, J.R., Rundlett, S.E., Suka, Y., Grunstein, M. Proc. Natl. Acad. Sci. U.S.A. (1999) [Pubmed]
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