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Gene Review

RIPK1  -  receptor (TNFRSF)-interacting serine...

Homo sapiens

Synonyms: Cell death protein RIP, RIP, RIP-1, RIP1, Receptor-interacting protein 1, ...
 
 
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Associations of RIPK1 with chemical compounds

  • We show that lysine 63-linked ubiquitination of RIP1 on lysine 377 inhibits TNF-induced apoptosis first through an NF-kappaB-independent mechanism and, subsequently, through an NF-kappaB-dependent mechanism [1].

References

  1. Ubiquitination of RIP1 regulates an NF-kappaB-independent cell-death switch in TNF signaling. O'Donnell, M.A., Legarda-Addison, D., Skountzos, P., Yeh, W.C., Ting, A.T. Curr. Biol. (2007) [Pubmed]
 
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