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Gene Review

orf6  -  ORF6

Streptococcus suis

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High impact information on orf6

  • In both strains, mega was integrated at the same site, an open reading frame identical to orf6 of Tn916 [1].
  • In the Tn1207.1-like transposon of these tet(O)-mef(A) elements, only msr(D) (orf5) and a modified orf6, in addition to mef(A), were detected by PCR in all isolates tested; while orf1 and orf2 were always undetectable, orf3, orf7 and orf8 were found in variable percentages [2].

Other interactions of orf6

  • There was no similarity between ORF3 and ORF6 and other protein sequences [3].


  1. Tn2009, a Tn916-like element containing mef(E) in Streptococcus pneumoniae. Del Grosso, M., Scotto d'Abusco, A., Iannelli, F., Pozzi, G., Pantosti, A. Antimicrob. Agents Chemother. (2004) [Pubmed]
  2. Distribution and molecular analysis of mef(A)-containing elements in tetracycline-susceptible and -resistant Streptococcus pyogenes clinical isolates with efflux-mediated erythromycin resistance. Brenciani, A., Ojo, K.K., Monachetti, A., Menzo, S., Roberts, M.C., Varaldo, P.E., Giovanetti, E. J. Antimicrob. Chemother. (2004) [Pubmed]
  3. Sequence analysis of a small cryptic plasmid isolated from Streptococcus suis serotype 2. Takamatsu, D., Osaki, M., Sekizaki, T. Curr. Microbiol. (2000) [Pubmed]
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